那他珠单抗治疗后多发性硬化患者脑脊液寡克隆区带消失
李海峰;洪宇;
摘要(Abstract)：
<正>脑脊液中的寡克隆区带(OB)是多发性硬化(MS)诊断的重要检验指标,一般认为MS患者OB可终生存在,提示中枢神经系统(CNS)内一直存在炎性反应。但IgG指数可于患者治疗好转后下降,提示CNS内的免疫反应强度减弱。OB亦可见于其他疾病,经治疗后可消失。MS患者OB能否消失?Mult Scler于2011年10月刊登的von Gle-hn等研究结果显示那他珠单抗治疗后MS患者脑脊液OB可以消失。
关键词(KeyWords)： 多发性硬化;那他珠单抗;寡克隆区带
基金项目(Foundation):
作者(Author): 李海峰;洪宇;
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DOI:
参考文献(References)：
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