抗NMDA受体脑炎
刘美云;谢琰臣;李继梅;
摘要(Abstract)：
抗N-甲基-M-天冬氨酸受体(N-methyl-D-aspartate receptor,NMDA)脑炎是一种与抗NMDA受体抗体相关的边缘叶脑炎(LE),其发病机制尚不清楚。该病常发生于伴有卵巢畸胎瘤的年轻女性患者,典型的临床表现为精神异常、痫性发作、意识障碍、中枢性通气不足、运动障碍以及自主神经功能紊乱,脑电图、头MRI一般无特异性表现,血及脑脊液抗NMDA受体抗体阳性。该病对包括肿瘤切除和免疫治疗在内的联合治疗敏感。此文对抗NMDA受体脑炎的发病机制、临床表现、诊断、治疗及预后做一综述。
关键词(KeyWords)： 边缘叶脑炎;抗N-甲基-M-天冬氨酸受体抗体;年轻女性;畸胎瘤
基金项目(Foundation):
作者(Author): 刘美云;谢琰臣;李继梅;
Email:
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