张蕊;潘晓丽;

• 1:中国医科大学附属盛京医院神经功能检查室

摘要(Abstract)：

目的探讨皮肤交感反应(sympathetic skin response,SSR)对2型糖尿病自主神经病变的诊断价值。方法对111例2型糖尿病患者及30例健康体检者进行SSR及神经传导速度测定,检测糖化血红蛋白(hemoglobin A1c,HbAlc)等多项生化指标,同时分析与SSR异常有关的因素。结果与对照组比较,病例组SSR潜伏期延长,波幅降低(P<0.05)。与病程<5年组比较,5～10年组、病程≥10年组上肢SSR潜伏期延长(P<0.05),而波幅变化无统计学差异(P>0.05)。各不同病程组间SSR异常率比较无统计学差异(P>0.05)。周围神经病变组SSR异常率高于无周围神经病变组(P<0.05),自主神经症状的有无对SSR异常率无影响(P>0.05)。Logistic回归分析结果显示,HbAlc是2型糖尿病患者SSR异常的相关因素。结论 SSR可早期发现糖尿病患者自主神经功能损害,HbAlc是2型糖尿病患者SSR异常的相关因素。

关键词(KeyWords)： 皮肤交感反应;2型糖尿病;自主神经病变;相关因素

Abstract:

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作者(Author): 张蕊;潘晓丽;

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