接种流感疫苗与Guillain-Barré综合征:与疫苗有关还是与流感病毒有关?
李海峰;周晓彬;
摘要(Abstract):
<正>20世纪70年代中期在美国发生了接种流感疫苗后Guillain-Barré综合征(Guillain-Barrésyndrome,GBS)发病率增高的情况。该事件促进了GBS的临床研究,20世纪80年代由美国学者制定了国际上第一个GBS诊断标准。直到21世纪初,学者们一直认为流感疫苗是引起GBS的一个重要因素。但近年研究提示流感病毒更可能是流感期
关键词(KeyWords): 流感疫苗;吉兰-巴雷综合征
基金项目(Foundation):
作者(Author): 李海峰;周晓彬;
Email:
DOI:
参考文献(References):
- [1]Liang XF,Li L,Liu DW,et al.Safety of influenza A(H1N1)vaccine in postmarketing surveillance in China[J].NEngl J Med,2011,364:638-647.
- [2]Cheng Q,Wang DS,Jiang GX,et al.Distinct pattern of age-specific incidence of Guillain-Barrésyndrome in Harbin,China[J].J Neurol,2002,249:25-32.
- [3]Zhang X,Zhang Z,Tang X.Guillain-Barre syndrome in sixcities and provinces of northern China:is it a new entity?[J].Chin Med J(Engl),1995,108:734-738.
- [4]Hurwitz ES,Schonberger LB,Nelson DB,et al.Guillain-Barrésyndrome and the 1978-1979influenza vaccine[J].NEngl J Med,1981,304:1557-1561.
- [5]Kaplan JE,Katona P,Hurwitz ES,et al.Guillain-Barrésyn-drome in the United States,1979-1980and 1980-1981.Lackof an association with influenza vaccination[J].JAMA,1982,248:698-700.
- [6]Hughes RA,Charlton J,Latinovic R,et al.No associationbetween immunization and Guillain-Barrésyndrome in the U-nited Kingdom,1992to 2000[J].Arch Intern Med,2006,166:1301-1304.
- [7]Burwen DR,Ball R,Bryan WW,et al.Evaluation of Guillain-BarréSyndrome among recipients of influenza vaccine in 2000and 2001[J].Am J Prev Med,2010,39:296-304.
- [8]Andrews N,Stowe J,Al-Shahi Salman R,et al.Guillain-Barrésyndrome and H1N1(2009)pandemic influenza vaccina-tion using an AS03adjuvanted vaccine in the United Kingdom:Self-controlled case series[J].Vaccine,2011,29(45):7878-7882.
- [9]Bardage C,Persson I,Ortqvist A,et al.Neurological and au-toimmune disorders after vaccination against pandemic influen-za A(H1N1)with a monovalent adjuvanted vaccine:popula-tion based cohort study in Stockholm,Sweden[J].BMJ,2011,343:d5956.
- [10]Vidal P,Reyna J,Saldana P,et al.Events temporarily asso-ciated with anti-influenza A(H1N1)vaccination in Mexico[J].Arch Med Res,2011,42(7):627-632.
- [11]Tam CC,O’Brien SJ,Petersen I,et al.Guillain-Barrésyn-drome and preceding infection with campylobacter,influenzaand Epstein-Barr virus in the general practice research data-base[J].PLoS One,2007,2:e344.
- [12]Sivadon-Tardy V,Orlikowski D,Porcher R,et al.Guillain-Barrésyndrome and influenza virus infection[J].Clin InfectDis,2009,48:48-56.
- [13]Stowe J,Andrews N,Wise L,et al.Investigation of the tem-poral association of Guillain-Barre syndrome with influenzavaccine and influenzalike illness using the United KingdomGeneral Practice Research Database[J].Am J Epidemiol,2009,169:382-388.
- [14]Grimaldi-Bensouda L,Alpérovitch A,Besson G,et al.Guil-lain-Barre syndrome,influenzalike illnesses,and influenzavaccination during seasons with and without circulating A/H1N1viruses[J].Am J Epidemiol,2011,174:326-335.
- [15]Dieleman J,Romio S,Johansen K,et al.Guillain-Barre syn-drome and adjuvanted pandemic influenza A(H1N1)2009vaccine:multinational case-control study in Europe[J].BMJ,2011,343:d3908.
- [16]Verity C,Stellitano L,Winstone AM,et al.Guillain-Barrésyndrome and H1N1influenza vaccine in UK children[J].Lancet,2011,378(9802):1545-1546.
- [17]Nachamkin I,Shadomy SV,Moran AP,et al.Anti-ganglio-side antibody induction by swine(A/NJ/1976/H1N1)andother influenza vaccines:insights into vaccine-associated Guil-lain-Barrésyndrome[J].J Infect Dis,2008,198:226-233.
- [18]Seale H,Heywood AE,McLaws ML,et al.Why do I needit?I am not at risk!Public perceptions towards the pandemic(H1N1)2009vaccine[J].BMC Infect Dis,2010,10:99.
- [19]Wong LP,Sam IC.Factors influencing the uptake of 2009H1N1influenza vaccine in a multiethnic Asian population[J].Vaccine,2010,28(28):4499-4505.
- [20]Liu S,Yuan H,Liu Y,et al.Attitudes of seasonal influenzavaccination among healthcare worker and general communitypopulation after pandemic influenza A/H1N1in Hangzhou[J].Hum Vaccin,2011,7(10):1072-1076.