帕金森病患者外周血T淋巴细胞亚群及红细胞免疫研究T Lymphocyte Subgroups and Erythrocyte Immune Function in Parkinson Disease Patients
雷革胜,苗建亭,李柱一
摘要(Abstract)：
目的 观察帕金森病 (PD)外周血 T淋巴细胞亚群和红细胞免疫功能。方法 应用直接免疫荧光染色法和免疫酵母菌花环法分别测定 2 0例 PD患者外周血 T淋巴细胞亚群和红细胞免疫功能 ,并对其中 1 0例服用 L-多巴前后进行比较。结果 病例组 CD3、CD4、CD8水平较对照组明显降低 ,而 RBC-ICR水平增高。治疗前后比较结果表明 ,服药后 CD3、CD8水平升高 ,RBC-ICR水平降低。结论 PD存在 T细胞免疫功能低下及循环中免疫复合物增多。应用多巴胺制剂可改善 PD的免疫学异常 ,提示 PD的免疫功能异常与体内多巴胺递质改变密切相关。
关键词(KeyWords)： 帕金森病;T淋巴细胞亚群;红细胞免疫
基金项目(Foundation):
作者(Author): 雷革胜,苗建亭,李柱一
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