脑梗死患者血清TNF-α、IL-1β含量的变化及其临床意义的研究Study on Changes of Serum Levels of Tumor Necrosis Factor-α and Interleukin-1β in Patients with Cerebral Infarction
陈明生,朱瑞芬,詹庆盈
摘要(Abstract)：
目的 了解脑梗死患者血清TNF α、IL 1β含量在恢复期和急性期的变化及意义。 方法 运用双抗夹心酶联免疫吸附法 (ELISA)测定血清中TNF α、IL 1β的含量。 结果 急性期、恢复期脑梗死患者血清TNF α、IL 1β水平较对照组显著增高 (P <0 .0 1) ,急性期又较恢复期高 (P <0 .0 5 ,P <0 .0 1) ;增高程度与神经功能缺损程度及梗死体积大小密切相关。结论 TNF α、IL 1β可能参与脑梗死早期的炎症反应及再灌注损伤 ,并在其中起重要作用。
关键词(KeyWords)： 脑梗死;肿瘤坏死因子;白介素1
基金项目(Foundation):
作者(Author): 陈明生,朱瑞芬,詹庆盈
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参考文献(References)：
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